(3S)-1-(2-Phenylethyl)-3-pyrrolidinamine → (S)-N-(1-(2-phenylethyl)pyrrolidin-3-yl)-7-norbornanecarboxamide

HRID 992316

반응식

HRID 992316 반응식
[CH:1]12[CH:7]([C:8]([OH:10])=O)[CH:4]([CH2:5][CH2:6]1)[CH2:3][CH2:2]2.[NH2:11][C@H:12]1[CH2:16][CH2:15][N:14]([CH2:17][CH2:18][C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)[CH2:13]1>>[C:19]1([CH2:18][CH2:17][N:14]2[CH2:15][CH2:16][C@H:12]([NH:11][C:8]([CH:7]3[CH:4]4[CH2:3][CH2:2][CH:1]3[CH2:6][CH2:5]4)=[O:10])[CH2:13]2)[CH:20]=[CH:21][CH:22]=[CH:23][CH:24]=1

참가 물질

3

반응물 2

HCID 10774056(3S)-1-(2-Phenylethyl)-3-pyrrolidinamineHCID 12757495Bicyclo(2.2.1)heptane-7-carboxylic acid

생성물 1

HCID 59915927(S)-N-(1-(2-phenylethyl)pyrrolidin-3-yl)-7-norbornanecarboxamide

실험 절차

7-Norbornanecarboxylic acid and (S)-3-amino-1-(2-phenylethyl)pyrrolidine were reacted under the same conditions as in Example 23 to give (S)-N-(1-(2-phenylethyl)pyrrolidin-3-yl)-7-norbornanecarboxamide.

출처 및 근거

ORD 기록
ord-664b4dcf6bc3484aae30e74d7e10bf5d
출처 데이터셋
uspto-grants-2002_10
특허 번호
US06468998B1

연결된 노트

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