Dichloromethane → 4-(4-Fluoropiperidin-1-yl)benzoic acid ethyl ester

반응식

[CH2:19]([N:20]([S:21]([F:22])([F:23])[F:25])[CH2:24][CH3:26])[CH3:27].[CH2:1]([CH3:2])[O:3][C:4]([c:5]1[cH:6][cH:7][c:8]([N:11]2[CH2:12][CH2:13][CH:14]([OH:17])[CH2:15][CH2:16]2)[cH:9][cH:10]1)=[O:18].[Cl:28][CH2:29][Cl:30]>>[CH2:1]([CH3:2])[O:3][C:4]([c:5]1[cH:6][cH:7][c:8]([N:11]2[CH2:12][CH2:13][CH:14]([F:25])[CH2:15][CH2:16]2)[cH:9][cH:10]1)=[O:18]

참가 물질

반응물 3

HCID 6344Dichloromethane

HCID 123472(Diethylamino)sulfur trifluoride

HCID 12717445Ethyl 4-(4-hydroxypiperidin-1-yl)benzoate

생성물 1

HCID 686494674-(4-Fluoropiperidin-1-yl)benzoic acid ethyl ester

출처 및 근거

ORD 기록: ord-f0257fecd6054e2fbc022dd6d8f667b2
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

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