Hexahydro-1,4-diazepine → HCID 10211347, 화합물

HRID 992988노트

반응식

HRID 992988 반응식
Cl[CH2:2][C:3]1[N:4]=[C:5]([C:8]2[CH:13]=[C:12]([O:14][CH3:15])[C:11]([O:16][CH3:17])=[C:10]([O:18][CH3:19])[CH:9]=2)[S:6][CH:7]=1.[NH:20]1[CH2:26][CH2:25][CH2:24][NH:23][CH2:22][CH2:21]1>>[CH3:19][O:18][C:10]1[CH:9]=[C:8]([C:5]2[S:6][CH:7]=[C:3]([CH2:2][N:20]3[CH2:26][CH2:25][CH2:24][N:23]([CH2:2][C:3]4[N:4]=[C:5]([C:8]5[CH:9]=[C:10]([O:18][CH3:19])[C:11]([O:16][CH3:17])=[C:12]([O:14][CH3:15])[CH:13]=5)[S:6][CH:7]=4)[CH2:22][CH2:21]3)[N:4]=2)[CH:13]=[C:12]([O:14][CH3:15])[C:11]=1[O:16][CH3:17]

참가 물질

3

반응물 2

HCID 68163Hexahydro-1,4-diazepineHCID 12010380HCID 12010380, 화합물

생성물 1

HCID 10211347HCID 10211347, 화합물

실험 절차

4-Chloromethyl-2-(3,4,5-trimethoxyphenyl)thiazole (198 mg) and homopiperazine (30 mg) were reacted in the same manner in Example 1 to obtain the title compound as a free base.

출처 및 근거

ORD 기록
ord-bd80d5d1eea8447d89942fead40b37e5
출처 데이터셋
uspto-grants-2002_10
특허 번호
US06472386B1

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