(2,6-Dimethoxypyridin-3-yl)boronic acid → 4-amino-N-cyclopropyl-7-fluoro-8-(2,6-dimethoxypyridin-3-yl)cinnoline-3-carboxamide

HRID 99418

반응식

HRID 99418 반응식
[CH3:20][O:21][c:22]1[n:23][c:24]([O:31][CH3:32])[cH:25][cH:26][c:27]1[B:28]([OH:29])[OH:30].[NH2:1][c:2]1[c:3]([C:14](=[O:15])[NH:16][CH:17]2[CH2:18][CH2:19]2)[n:4][n:5][c:6]2[c:7]([I:13])[c:8]([F:12])[cH:9][cH:10][c:11]12>>[NH2:1][c:2]1[c:3]([C:14](=[O:15])[NH:16][CH:17]2[CH2:18][CH2:19]2)[n:4][n:5][c:6]2[c:7](-[c:27]3[c:22]([O:21][CH3:20])[n:23][c:24]([O:31][CH3:32])[cH:25][cH:26]3)[c:8]([F:12])[cH:9][cH:10][c:11]12

참가 물질

3

반응물 2

HCID 2762707(2,6-Dimethoxypyridin-3-yl)boronic acidHCID 672285864-amino-7-fluoro-8-iodo-N-cyclopropyl-cinnoline-3-carboxamide

생성물 1

HCID 251832714-amino-N-cyclopropyl-7-fluoro-8-(2,6-dimethoxypyridin-3-yl)cinnoline-3-carboxamide

출처 및 근거

ORD 기록
ord-d5339837fe644e5b8793dd8f589eaa78
출처 데이터셋
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

연결된 노트

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