Ethyl 3-methyl-5-(2-oxo-3-(4-(trifluoromethyl)benzyl)imidazolidin-1-yl)thiophene-2-carboxylate → 5-(3-(4-Fluorobenzyl)-2-oxoimidazolidin-1-yl)-3-methylthiophene-2-carboxylic acid
Reaction equation
[CH3:1][c:2]1[cH:3][c:4]([N:5]2[CH2:6][CH2:7][N:8]([CH2:9][c:10]3[cH:11][cH:12][c:13]([C:14]([F:15])([F:16])[F:17])[cH:18][cH:19]3)[C:20]2=[O:21])[s:22][c:23]1[C:24]([O:25][CH2:26][CH3:27])=[O:28].[F:29][c:30]1[cH:31][cH:32][c:33]([CH2:34][N:35]2[C:36](=[O:51])[N:37]([c:40]3[cH:41][c:42]([CH3:50])[c:43]([C:45](=[O:46])[O:47][CH2:48][CH3:49])[s:44]3)[CH2:38][CH2:39]2)[cH:52][cH:53]1>>[F:29][c:30]1[cH:31][cH:32][c:33]([CH2:34][N:35]2[C:36](=[O:51])[N:37]([c:40]3[cH:41][c:42]([CH3:50])[c:43]([C:45](=[O:46])[OH:47])[s:44]3)[CH2:38][CH2:39]2)[cH:52][cH:53]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-05e9209d4ea24d35a07c7c9b7f72331e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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