Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 100223Generated: October 26, 2026

Acetic Acid → 8-(2-Methyl-thiazole-4-carbonyl)-2-(4-trifluoromethoxy-phenyl)-2,8-diaza-spiro[4.5]decan-1-one

https://huagongshe.com/reaction/100223

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetic AcidHCID 176—
ReactantHydrochloric AcidHCID 313—
Reactant2-Methyl-1,3-thiazole-4-carbonyl chlorideHCID 21183959—
Reactant2-(4-(Trifluoromethoxy)phenyl)-2,8-diazaspiro[4.5]decan-1-oneHCID 66742759—
Product8-(2-Methyl-thiazole-4-carbonyl)-2-(4-trifluoromethoxy-phenyl)-2,8-diaza-spiro[4.5]decan-1-oneHCID 59577981—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (2/10)
ORD IDord-6b2c5188e59d490780ed815e55d37922
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (2/10)