Dichloromethane → 5-Chloro-1-(1-cyclopropyl-2-hydroxyethyl)-3-[[6-(difluoromethoxy)-2,5-dimethyl-3-pyridinyl]amino]pyrazin-2-one
Reaction equation
[B:29]([Br:30])([Br:31])[Br:32].[Cl:1][c:2]1[n:3][c:4]([NH:16][c:17]2[c:18]([CH3:28])[n:19][c:20]([O:24][CH:25]([F:26])[F:27])[c:21]([CH3:23])[cH:22]2)[c:5](=[O:15])[n:6]([CH:8]([CH2:9][O:10][CH3:11])[CH:12]2[CH2:13][CH2:14]2)[cH:7]1.[Cl:33][CH2:34][Cl:35]>>[Cl:1][c:2]1[n:3][c:4]([NH:16][c:17]2[c:18]([CH3:28])[n:19][c:20]([O:24][CH:25]([F:26])[F:27])[c:21]([CH3:23])[cH:22]2)[c:5](=[O:15])[n:6]([CH:8]([CH2:9][OH:10])[CH:12]2[CH2:13][CH2:14]2)[cH:7]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-0e7198355c2c42179348498aa3e8f6e8
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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