反应详情

51.5 g (500 mmol) of diethylenetriamine and 139 ml (1 mol) of triethylamine are dissolved in dichloromethane and mixed at -20° C. with 161 g of benzyl cyanoformate (Fluka) in dichloromethane and then stirred overnight at room temperature. After the reaction is completed, concentration by evaporation is performed during draw-off, the residue is taken up in diethyl ether, the organic phase is washed with sodium carbonate solution and dried with sodium sulfate. The filtrate is mixed with hexane, and the precipitate is filtered off and dried.

1. concentrationconcentration
2. customby evaporation
3. washthe organic phase is washed with sodium carbonate solution
4. dry with materialdried with sodium sulfate
5. additionThe filtrate is mixed with hexane
6. filtrationthe precipitate is filtered off
7. customdried