N-(11-(Carbomethoxy)undecanoyl)-N-Methyl-2-Benzyloxyaniline → N-(11-(Carbomethoxy)undecanoyl)-N-Methyl-2-Hydroxy aniline

HRID 1003245Notes

Reaction equation

HRID 1003245 reaction equation
[C:1]([CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][C:15]([N:17]([CH3:32])[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][C:19]=1[O:24]CC1C=CC=CC=1)=[O:16])([O:3][CH3:4])=[O:2].[H][H]>CO.[Pd]>[C:1]([CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][C:15]([N:17]([CH3:32])[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][C:19]=1[OH:24])=[O:16])([O:3][CH3:4])=[O:2]

Participants

5

Reactant 2

HCID 18795814N-(11-(Carbomethoxy)undecanoyl)-N-Methyl-2-BenzyloxyanilineHCID 178418361HCID 178418361, compound

Product 1

HCID 54429764N-(11-(Carbomethoxy)undecanoyl)-N-Methyl-2-Hydroxy aniline

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

A solution of (28) (0.11 g., 0.25 mM) in methanol (11 mL) containing 10% palladium on carbon (30 mg.) is shaken in a 40 p.s.i. hydrogen atmosphere until no (V) remained (TLC analysis). The filtered solution was then concentrated in vacuo to give the title compound (29), used immediately in step P.

Workup

  1. concentrationThe filtered solution was then concentrated in vacuo

Sources & evidence

ORD record
ord-68dacbd0580d445589cd8e68270bbd3f
Source dataset
uspto-grants-2000_04
Patent number
US06046183

Reaction notes

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