Hydrogen Bromide → 12-Bromo-1-dodecanol

Participants

Reaction Steps

To 30.25 g of 1,12-dodecanediol were added 350 ml of toluene and 52 ml of 48% hydrobromic acid and the mixture was heated under reflux under azeotropic condition for 2 hours. The reaction solution was cooled and the starting material precipitated out was filtered off. The filtrate was distilled and recrystallized from hexane to afford 30.2 g of the title compound as a crystal.

Provenance & Evidence