Benzyl(methoxymethyl)((trimethylsilyl)methyl)amine → HCID 15391234, compound

HRID 1003410Notes

Reaction equation

HRID 1003410 reaction equation
[CH3:1][O:2][C:3]1[CH:12]=[CH:11][CH:10]=[C:9]2[C:4]=1[CH:5]=[CH:6][C:7](=O)[O:8]2.CO[CH2:16][N:17](CC1C=CC=CC=1)[CH2:18][Si](C)(C)C>>[CH3:1][O:2][C:3]1[C:4]2[C@@H:5]3[CH2:18][NH:17][CH2:16][C@@H:6]3[CH2:7][O:8][C:9]=2[CH:10]=[CH:11][CH:12]=1

Participants

3

Reactant 2

HCID 353442Benzyl(methoxymethyl)((trimethylsilyl)methyl)amineHCID 108991915-METHOXYCOUMARIN

Product 1

HCID 15391234HCID 15391234, compound

Procedure

From 5-methoxycoumarin and N-methoxymethyl-N-trimethylsilylmethyl-benzylamine in an analogous manner as described in Examples 1A-C. 1H NMR (300 MHz, CDCl3) δ 2.55 (m, 1H), 2.67 (dd, 1H), 2.80 (dd, 1H), 3.21 (q, 1H), 3.32 (dd, 1H), 3.62 (dd, 1H), 3.70 (m, 1H), 3.81 (s, 3H), 4.10 (dd, 1H), 6.46 (d, 1H), 6.55 (d, 1H), 7.17 (t, 1H).

Sources & evidence

ORD record
ord-771d61223b974c2aad653a33e59140e7
Source dataset
uspto-grants-2000_04
Patent number
US06046207

Reaction notes

Loading…