Dimethylamine → HCID 12968693, compound

Participants

Reaction Steps

In a similar method to that of Example 16, methyl 3-(3-cyano-1,2-dihydro-2-oxo-6-pyridinyl)-4-propoxybenzoate (2.14 g) was saponified, converted into the acid chloride and treated with dimethylamine to give 2.0 g of a solid. This was combined with a further 0.2 g obtained in a similar manner, and purified by flash chromatography to give 1.9 g of solid m.p. 201-202° C. Recrystallization of part of this gave the title compound, m.p. 214-215° C.

Provenance & Evidence