1,3,4,5-Tetrahydro-2H-1-benzazepin-2-one → HCID 18428530, compound

HRID 1003448Notes

Reaction equation

HRID 1003448 reaction equation
[NH:1]1[C:7]2[CH:8]=[CH:9][CH:10]=[CH:11][C:6]=2[CH2:5][CH2:4][CH2:3][C:2]1=[O:12].F[B-](F)(F)F.[CH3:18][O+](C)C>>[CH3:18][O:12][C:2]1[CH2:3][CH2:4][CH2:5][C:6]2[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=2[N:1]=1

Participants

3

Reactant 2

HCID 2485801,3,4,5-Tetrahydro-2H-1-benzazepin-2-oneHCID 2735153Oxonium, trimethyl-, tetrafluoroborate(1-) (1:1)

Product 1

HCID 18428530HCID 18428530, compound

Procedure

A sample of the title compound of EXAMPLE 165 (3.2 g, 20.0 mmol) was reacted with trimethyloxonium tetrafluoroborate (4.4 g, 30.0 mmol) by the method of EXAMPLE 26 to yield, after chromatography, 2.5 g (73%) of the title material.

Workup

  1. customto yield

Sources & evidence

ORD record
ord-7ab10024d02145588c246e6b199ceff8
Source dataset
uspto-grants-2000_04
Patent number
US06046211

Reaction notes

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