Ammonium Chloride → HCID 178442371, compound

HRID 1003455Notes

Reaction equation

HRID 1003455 reaction equation
[CH2:1]([CH:3]([CH2:14][CH3:15])[CH2:4][CH:5]1[CH2:11][CH2:10][CH2:9][CH2:8][C:7](OC)=[N:6]1)[CH3:2].[Cl-:16].[NH4+:17]>CO>[ClH:16].[CH2:1]([CH:3]([CH2:14][CH3:15])[CH2:4][CH:5]1[NH:6][C:7](=[NH:17])[CH2:8][CH2:9][CH2:10][CH2:11]1)[CH3:2]

Participants

4

Reactant 2

HCID 25517Ammonium ChlorideHCID 10750993HCID 10750993, compound

Product 1

HCID 178442371HCID 178442371, compoundYield 57.8%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

The product of EXAMPLE 196 (470 mg, 2.2 mmol) in 18 mL of MeOH was reacted with ammonium chloride (98 mg, 1.8 mmol) by the method of EXAMPLE 27 to yield 242 mg of the title material.

Sources & evidence

ORD record
ord-1bba451d7e6e4a8c97eede5159354f1a
Source dataset
uspto-grants-2000_04
Patent number
US06046211

Reaction notes

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