5-Butylpyridin-2-amine → HCID 178476211, compound

HRID 1003489Notes

Reaction equation

HRID 1003489 reaction equation
[C:1]([OH:4])(=[O:3])[CH3:2].N=C1CC(C)CCN1.[NH2:13][C:14]1[CH:19]=[CH:18][C:17]([CH2:20][CH2:21][CH2:22][CH3:23])=[CH:16][N:15]=1>>[C:1]([OH:4])(=[O:3])[CH3:2].[NH:13]=[C:14]1[CH2:19][CH2:18][CH:17]([CH2:20][CH2:21][CH2:22][CH3:23])[CH2:16][NH:15]1

Participants

3

Reactant 2

HCID 184286505-Butylpyridin-2-amineHCID 1784758702-Imino-4-methylpiperidine acetate

Product 1

HCID 178476211HCID 178476211, compound

Procedure

The method of preparation of 2-imino-4-methylpiperidine acetate was used to convert 2-amino-5-(n-butyl)pyridine to the title compound except platinum oxide was used as the catalyst. Product was triturated with ether to give a white solid. The analysis of the product was found to be consistent with the proposed structure. MH+=155; 1H NMR (D2O): δ3.35-3.25 (m, 1H); 2.85-2.75 (m, 1H); 2.60-2.35 (m, 2H); 1.85-1.55 (m, 2H); 1.75 (s, 3H); 1.35-1.05 (m, 7H); 0.75-0.65 (m, 3H).

Sources & evidence

ORD record
ord-25bed92e1e894a0c923897d452f688e8
Source dataset
uspto-grants-2000_04
Patent number
US06046211

Reaction notes

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