N-ethyl-4-methylpyridin-2-amine → HCID 178476385, compound

HRID 1003495Notes

Reaction equation

HRID 1003495 reaction equation
[C:1]([OH:4])(=[O:3])[CH3:2].N=C1CC(C)CCN1.[CH2:13]([NH:15][C:16]1[CH:21]=[C:20]([CH3:22])[CH:19]=[CH:18][N:17]=1)[CH3:14]>>[C:1]([OH:4])(=[O:3])[CH3:2].[CH3:14][CH2:13][N:15]=[C:16]1[CH2:21][CH:20]([CH3:22])[CH2:19][CH2:18][NH:17]1

Participants

3

Reactant 2

HCID 18428456N-ethyl-4-methylpyridin-2-amineHCID 1784758702-Imino-4-methylpiperidine acetate

Product 1

HCID 178476385HCID 178476385, compound

Procedure

The method of preparation of 2-imino-4-methylpiperidine acetate was used to convert 2-(ethylamino)-4-methylpyridine to the title compound except platinum oxide was used as the catalyst. The analysis of the product, obtained as an oil, was found to be consistent with the proposed structure. MH+=141; 1H NMR (D2O): δ3.40-3.10 (m, 2H); 3.00 (q, J=6 Hz, 2H); 2.50-2.40 (m, 1H); 2.10-1.90 (m, 1H); 1.83 (s, 3H); 1.80-1.65 (m, 4H); 1.40-1.20 (m, 1H); 1.02 (t, J=6 Hz, 3H); 0.83 (d, J=6 Hz, 3H).

Sources & evidence

ORD record
ord-b6953f55547744759e84cb05c5e3ad8f
Source dataset
uspto-grants-2000_04
Patent number
US06046211

Reaction notes

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