HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Fluoroindole → 5-fluoro-3-(1-methyl-1,2,3,6-tetrahydro-4-pyridinyl)-1H-indole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Fluoroindole | HCID 67861 | — |
| Reactant | 1-Methyl-4-piperidone | HCID 74049 | — |
| Product | 5-fluoro-3-(1-methyl-1,2,3,6-tetrahydro-4-pyridinyl)-1H-indole | HCID 14973209 | 94% |
Reaction Steps
Beginning with 1.00 gm (7.4 mMol) 5-fluoro-1H-indole and 1.82 mL (14.8 mMol) 1-methyl-4-piperidone, 1.60 gm (94%) of the title compound were recovered as a crystalline solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06046215 |
| Source dataset | uspto-grants-2000_04 |
| ORD ID | ord-b8cb0995fe2a413795b8679045a18aba |
| Source note | uspto-grants-2000_04 |