1-Methyl-4-piperidone → HCID 23288132, compound

HRID 1003547Notes

Reaction equation

HRID 1003547 reaction equation
[Cl:1][C:2]1[CH:10]=[C:9]2[C:5]([CH:6]=[CH:7][NH:8]2)=[CH:4][CH:3]=1.[CH3:11][N:12]1[CH2:17][CH2:16][C:15](=O)[CH2:14][CH2:13]1>>[Cl:1][C:2]1[CH:10]=[C:9]2[C:5]([C:6]([C:15]3[CH2:16][CH2:17][N:12]([CH3:11])[CH2:13][CH:14]=3)=[CH:7][NH:8]2)=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 740491-Methyl-4-piperidoneHCID 871116-Chloroindole

Product 1

HCID 23288132HCID 23288132, compoundYield 104.4%

Procedure

Beginning with 1.00 gm (6.6 mmol) 6-chloro-1H-indole and 1.6 mL (13.0 mMol) 1-methyl-4-piperidone, 1.7 gm (100%) of the title compound were recovered as a pale yellow solid.

Sources & evidence

ORD record
ord-70a5af545f7c49049723d8727d06cd3e
Source dataset
uspto-grants-2000_04
Patent number
US06046215

Reaction notes

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