Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1003548Generated: October 25, 2026

1-Methyl-4-piperidone → 7-chloro-3-(1-methyl-1,2,3,6-tetrahydropyridin-4-yl)-1H-indole

https://huagongshe.com/reaction/1003548

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Methyl-4-piperidoneHCID 74049—
Reactant7-chloro-1H-indoleHCID 104644—
Product7-chloro-3-(1-methyl-1,2,3,6-tetrahydropyridin-4-yl)-1H-indoleHCID 1879723581.1%

Reaction Steps

Beginning with 0.50 gm (3.3 mMol) 7-chloro-1H-indole and 0.81 mL (6.6 mMol) 1-methyl-4-piperidone, 0.66 gm (81%) of the title compound were recovered as a white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06046215
Source datasetuspto-grants-2000_04
ORD IDord-f010716397d840d7aceb336b3fca2edf
Source noteuspto-grants-2000_04