HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Fluoroindole → 5-fluoro-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Fluoroindole | HCID 67861 | — |
| Reactant | Piperonylamine | HCID 2723901 | — |
| Product | 5-fluoro-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole | HCID 11344959 | 72% |
Reaction Steps
Beginning with 4.0 gm (29.6 mMol) 5-fluoro-1H-indole and 9.13 gm (59.0 mMol) 4-piperidone hydrochloride monohydrate, 4.60 gm (72%) of the title compound were recovered as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06046215 |
| Source dataset | uspto-grants-2000_04 |
| ORD ID | ord-04b10b04f47e4622b1ef79ca426fc680 |
| Source note | uspto-grants-2000_04 |