HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Fluoroindole → 6-fluoro-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Fluoroindole | HCID 351278 | — |
| Reactant | Piperonylamine | HCID 2723901 | — |
| Product | 6-fluoro-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole | HCID 11053072 | 59.1% |
Reaction Steps
Beginning with 11.6 gm (86.0 mMol) 6-fluoro-1H-indole and 26.5 gm (172 mMol) 4-piperidone hydrochloride monohydrate, 11.0 gm (59%) of the title compound were recovered as a light tan solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06046215 |
| Source dataset | uspto-grants-2000_04 |
| ORD ID | ord-7d43a47a4e834654a9c777a9f53d17bf |
| Source note | uspto-grants-2000_04 |