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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1003558Generated: October 25, 2026

Piperonylamine → 7-Fluoro-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole

https://huagongshe.com/reaction/1003558

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPiperonylamineHCID 2723901—
Reactant7-Fluoro-1H-indoleHCID 2774504—
Product7-Fluoro-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indoleHCID 1208345366%

Reaction Steps

Beginning with 2.0 gm (14.8 mMol) 7-fluoro-1H-indole and 4.6 gm (30.0 mMol) 4-piperidone hydrochloride monohydrate, 2.1 gm (66%) of the title compound were recovered as a white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06046215
Source datasetuspto-grants-2000_04
ORD IDord-2994a95059174121bad2d407ee608b68
Source noteuspto-grants-2000_04