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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1003565Generated: October 30, 2026

5-Methoxyindole → 5-Methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1H indole

https://huagongshe.com/reaction/1003565

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-MethoxyindoleHCID 13872—
ReactantPiperonylamineHCID 2723901—
Product5-Methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1H indoleHCID 10802979%

Reaction Steps

Beginning with 5.0 gm (34.0 mmol) 5-methoxy-1H-indole and 10.0 gm (65.0 mMol) 4-piperidone hydrochloride monohydrate, 6.1 gm (79%) of the title compound were recovered as a yellow solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06046215
Source datasetuspto-grants-2000_04
ORD IDord-cbdb71a70ea64fdc9d322a14ab771ace
Source noteuspto-grants-2000_04