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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1003566Generated: October 31, 2026

6-Methoxy-1H-indole → 6-methoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole

https://huagongshe.com/reaction/1003566

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-Methoxy-1H-indoleHCID 76659—
ReactantPiperonylamineHCID 2723901—
Product6-methoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indoleHCID 1301900590%

Reaction Steps

Beginning with 2.0 gm (14.0 mMol) 6-methoxy-1H-indole and 4.2 gm (27.0 mMol) 4-piperidone hydrochloride monohydrate, 2.8 gm (90%) of the title compound were recovered as a yellow solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06046215
Source datasetuspto-grants-2000_04
ORD IDord-d3ef6eb1ec3745f8ad259d7f2e2fc0af
Source noteuspto-grants-2000_04