Piperonylamine → HCID 18797408, compound

HRID 1003569Notes

Reaction equation

HRID 1003569 reaction equation
[CH:1]1([C:4]2[CH:5]=[CH:6][CH:7]=[C:8]3[C:12]=2[NH:11][CH:10]=[CH:9]3)[CH2:3][CH2:2]1.O.Cl.[NH:15]1[CH2:20][CH2:19][C:18](=O)[CH2:17][CH2:16]1>>[CH:1]1([C:4]2[CH:5]=[CH:6][CH:7]=[C:8]3[C:12]=2[NH:11][CH:10]=[C:9]3[C:18]2[CH2:19][CH2:20][NH:15][CH2:16][CH:17]=2)[CH2:3][CH2:2]1

Participants

3

Reactant 2

HCID 2723901PiperonylamineHCID 18797227HCID 18797227, compound

Product 1

HCID 18797408HCID 18797408, compoundYield 55%

Procedure

Beginning with 2.0 gm (12.7 mMol) 7-cyclopropyl-1H-indole and 3.9 gm (25.0 mmol) 4-piperidone hydrochloride monohydrate, 1.66 gm (55%) of the title compound were recovered as a white solid.

Sources & evidence

ORD record
ord-7dcf2583511f4e3a8d0859e40f661720
Source dataset
uspto-grants-2000_04
Patent number
US06046215

Reaction notes

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