Acetone → HCID 15428864, compound

Participants

Reaction Steps

To a solution of 19 g (91 millimoles) of ethyl-4-(2-chloroethoxy)-acetoacetate (IV) and 380 ml of acetone 134.4 g (910 millimoles) of sodium iodide are added. The reaction mixture is heated to boiling for 13 hours. The inorganic substance is filtered off and the filtrate is evaporated in vacuo. The residual oil is dissolved in dichloro methane, the solution is washed with water, dried and evaporated. The crude product is subjected to fractionated distillation in vacuo. Bp.: 170° C./0.1 Hgmm. Thus 18.3 g of the desired product are obtained, yield 67%.

Provenance & Evidence