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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 1003817Erstellt: 25. Oktober 2026

Imidazole → 1-{4-[2-(tert-Butyl-dimethyl-silanyloxy)-ethoxy]-phenyl}-3-phenyl-propan-1-one

https://huagongshe.com/reaction/1003817

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktImidazoleHCID 795—
Edukttert-Butyldimethylsilyl chlorideHCID 28928—
Edukt1-[4-(2-Hydroxy-ethoxy)-phenyl]-3-phenyl-propan-1-oneHCID 18798689—
LösungsmittelDichloromethaneHCID 6344—
Produkt1-{4-[2-(tert-Butyl-dimethyl-silanyloxy)-ethoxy]-phenyl}-3-phenyl-propan-1-oneHCID 18798693—

Reaktionsschritte

The title compound was prepared as described in General Method 5 using 1-[4-(2-hydroxy-ethoxy)-phenyl]-3-phenyl-propan-1-one from Example N (2.21 g, 8.2 mmol), imidazole (0.67 g, 9.8 mmol), t-butyldimethylsilyl chloride (1.36 g, 9.0 mmol) and CH2Cl2 (70 mL). The product was carried on crude to the next step (see Example SS.)

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS06046355
Quelldatensatzuspto-grants-2000_04
ORD IDord-08bc70e74df84637afb50fbb97b1c601
Quellennotizuspto-grants-2000_04