HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Imidazole → 1-{4-[2-(tert-Butyl-dimethyl-silanyloxy)-ethoxy]-phenyl}-3-phenyl-propan-1-one
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Imidazole | HCID 795 | — |
| Edukt | tert-Butyldimethylsilyl chloride | HCID 28928 | — |
| Edukt | 1-[4-(2-Hydroxy-ethoxy)-phenyl]-3-phenyl-propan-1-one | HCID 18798689 | — |
| Lösungsmittel | Dichloromethane | HCID 6344 | — |
| Produkt | 1-{4-[2-(tert-Butyl-dimethyl-silanyloxy)-ethoxy]-phenyl}-3-phenyl-propan-1-one | HCID 18798693 | — |
Reaktionsschritte
The title compound was prepared as described in General Method 5 using 1-[4-(2-hydroxy-ethoxy)-phenyl]-3-phenyl-propan-1-one from Example N (2.21 g, 8.2 mmol), imidazole (0.67 g, 9.8 mmol), t-butyldimethylsilyl chloride (1.36 g, 9.0 mmol) and CH2Cl2 (70 mL). The product was carried on crude to the next step (see Example SS.)
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06046355 |
| Quelldatensatz | uspto-grants-2000_04 |
| ORD ID | ord-08bc70e74df84637afb50fbb97b1c601 |
| Quellennotiz | uspto-grants-2000_04 |