HuagongsheHuagongshe Chemistry Print Report · For research reference only
Imidazole → 4-(4-tert-Butyldimethylsilyloxy-phenyl)-2-butanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Imidazole | HCID 795 | — |
| Reactant | 4-(4'-Hydroxyphenyl)-2-butanone | HCID 21648 | — |
| Reactant | tert-Butyldimethylsilyl chloride | HCID 28928 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 4-(4-tert-Butyldimethylsilyloxy-phenyl)-2-butanone | HCID 18798666 | — |
Reaction Steps
The title compound was prepared as described in General Method 5 using 10 g (60.9 mmol) of 4-(4-hydroxyphenyl)-2-butanone, 10.1 g (67 mmol) of tert-butyldimethyl silyl chloride, 4.56 g (67 mmol) of imidazole and 150 mL of DMF. The crude product was carried on "as is" to the next step (see Example KK).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06046355 |
| Source dataset | uspto-grants-2000_04 |
| ORD ID | ord-9e0343a3a4e04917aa1b04e4dbdc088b |
| Source note | uspto-grants-2000_04 |