Acrylic Acid → HCID 18794236, compound

Participants

Reaction Steps

Acrylic acid (0.23 mL) is added to a solution of 7-ethyl-6-methoxy-1-methyl-3,4-dihydro-β-carboline (740 mg, 3.05 mmol) in DMF (6 mL), followed by dropwise addition of diphenylphosphoryl azide dissolved in DMF (1.5 mL). The medium is left stirring for 6 h. Separation on silica gel allows the 9-methoxy-10-ethyl-2,3,4,6,7,12-hexahydroindolo[2,3-a]quinolizin4-one to be recovered (23% yield).

Provenance & Evidence