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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1004131Generated: October 26, 2026

(E)-1-[3-(4-hydroxy-3-methoxyphenyl)-2-propenyl]-4-(4-phenoxyphenyl)piperidine → (E)-1-[3-(4-fluorophenyl)-2-propenyl]-4-(4-phenoxyphenyl)piperidine

https://huagongshe.com/reaction/1004131

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(E)-1-[3-(4-hydroxy-3-methoxyphenyl)-2-propenyl]-4-(4-phenoxyphenyl)piperidineHCID 18412177—
Reactant4-Fluorocinnamyl bromideHCID 54481317—
Product(E)-1-[3-(4-fluorophenyl)-2-propenyl]-4-(4-phenoxyphenyl)piperidineHCID 18412141—

Reaction Steps

The same procedure was followed as in Example 11 using the compound (9) synthesized in Example 2 and 4-fluorocinnamyl bromide to produce the above.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06048876
Source datasetuspto-grants-2000_04
ORD IDord-7f5cbb2f98c04da28346dc0e3a1b4068
Source noteuspto-grants-2000_04