Bromomethylstyrene → HCID 18794490, compound
Reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=2[C:15]2[CH2:16][CH2:17][NH:18][CH2:19][CH:20]=2)=[CH:4][CH:3]=1.[CH2:21](Br)[CH:22]=[CH:23][C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1>>[F:1][C:2]1[CH:3]=[CH:4][C:5]([CH2:8][C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=2[C:15]2[CH2:20][CH2:19][N:18]([CH2:21]/[CH:22]=[CH:23]/[C:24]3[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=3)[CH2:17][CH:16]=2)=[CH:6][CH:7]=1Participants
3
Procedure
The same procedure was followed as in Example 11 using 4-[2-(4-fluorophenyl)methylphenyl]-1,2,3,6-tetrahydropyridine and cinnamyl bromide to produce the above.
Workup
- customto produce the above
Sources & evidence
- ORD record
- ord-04414f238d5c43cc9b2e57bd5d629530
- Source dataset
- uspto-grants-2000_04
- Patent number
- US06048876
Reaction notes
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