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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1004136Generated: October 27, 2026

1-[4-[(4-Fluorophenyl)methyl]phenyl]piperazine → (E)-1-[4-(4-fluorophenyl)methylphenyl]-4-[3-(4-fluorophenyl)-2-propenyl]piperazine

https://huagongshe.com/reaction/1004136

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-[4-[(4-Fluorophenyl)methyl]phenyl]piperazineHCID 1519998—
Reactant4-Fluorocinnamyl bromideHCID 54481317—
Product(E)-1-[4-(4-fluorophenyl)methylphenyl]-4-[3-(4-fluorophenyl)-2-propenyl]piperazineHCID 18794492—

Reaction Steps

The same procedure was followed as in Example 11 using the compound (10) synthesized in Example 3 and 4-fluorocinnamyl bromide to produce the above.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06048876
Source datasetuspto-grants-2000_04
ORD IDord-00d91873a4fb4068a874962fe11dadf0
Source noteuspto-grants-2000_04