1-[4-[(4-Fluorophenyl)methyl]phenyl]piperazine → HCID 18794501, compound

HRID 1004137Notes

Reaction equation

HRID 1004137 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][C:9]2[CH:14]=[CH:13][C:12]([N:15]3[CH2:20][CH2:19][NH:18][CH2:17][CH2:16]3)=[CH:11][CH:10]=2)=[CH:4][CH:3]=1.[F:21][C:22]1[CH:27]=[CH:26][C:25]([O:28][CH2:29][CH2:30][CH2:31][CH2:32]Br)=[CH:24][CH:23]=1>>[F:21][C:22]1[CH:27]=[CH:26][C:25]([O:28][CH2:29][CH2:30][CH2:31][CH2:32][N:18]2[CH2:17][CH2:16][N:15]([C:12]3[CH:13]=[CH:14][C:9]([CH2:8][C:5]4[CH:4]=[CH:3][C:2]([F:1])=[CH:7][CH:6]=4)=[CH:10][CH:11]=3)[CH2:20][CH2:19]2)=[CH:24][CH:23]=1

Participants

3

Reactant 2

HCID 15199981-[4-[(4-Fluorophenyl)methyl]phenyl]piperazineHCID 71722951-(4-Bromobutoxy)-4-fluorobenzene

Product 1

HCID 18794501HCID 18794501, compound

Procedure

The same procedure was followed as in Example 11 using the compound (10) synthesized in Example 3 and 4-(4-fluorophenyl)oxybutyl bromide to produce the above.

Workup

  1. customto produce the above

Sources & evidence

ORD record
ord-415dd1ce1f844265bd52927ea88c1ed8
Source dataset
uspto-grants-2000_04
Patent number
US06048876

Reaction notes

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