HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 4-chloroacetoacetate → Methyl 2-[2-(benzylamino)-1,3-thiazol-4-yl]acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 4-chloroacetoacetate | HCID 36240 | — |
| Reactant | N-(Phenylmethyl)thiourea | HCID 737375 | — |
| Product | Methyl 2-[2-(benzylamino)-1,3-thiazol-4-yl]acetate | HCID 2418839 | 105.1% |
Reaction Steps
1.87 g of N-benzylthiourea and 1.82 g of methyl 4-chloroacetoacetate were subjected to a cyclization reaction to obtain 3.10 g of methyl (2-benzylaminothiazol-4-yl)acetate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06048884 |
| Source dataset | uspto-grants-2000_04 |
| ORD ID | ord-cbb404ffee534cf0bf15dca03b9e3b31 |
| Source note | uspto-grants-2000_04 |