化工社化工社 化学情報印刷レポート · 研究参考用
Benzeneethanamine, 4-nitro-, hydrochloride (1:1) → (s)-1-Phenoxy-3-[[2-(4-nitrophenyl)ethyl]amino]-2-propanol
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Benzeneethanamine, 4-nitro-, hydrochloride (1:1) | HCID 458983 | — |
| 反応物 | (2S)-2-(phenoxymethyl)oxirane | HCID 1534345 | — |
| 溶媒 | Triethylamine | HCID 8471 | — |
| 生成物 | (s)-1-Phenoxy-3-[[2-(4-nitrophenyl)ethyl]amino]-2-propanol | HCID 53932073 | 39.3% |
反応手順
7.71 g of (S)-2-phenoxymethyloxirane and 10.34 g of 2-(4-nitrophenyl)ethylamine hydrochloride were subjected to a ring-opening reaction in the presence of 5.20 g of triethylamine to obtain 6.35 g of (S)-1-phenoxy-3-[[2-(4-nitrophenyl)ethyl]amino]-2-propanol.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06048884 |
| 出典データセット | uspto-grants-2000_04 |
| ORD ID | ord-3fc1cd3718d74780b264af58b6f8fd4d |
| 出典メモ | uspto-grants-2000_04 |