Tert-butyl 4-aminophenethylcarbamate → HCID 54309575, compound

HRID 1004154Notes

Reaction equation

HRID 1004154 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][CH2:9][NH:10][C:11](=[O:17])[O:12][C:13]([CH3:16])([CH3:15])[CH3:14])=[CH:4][CH:3]=1.[CH2:18]([NH:25][C:26]1[S:27][CH:28]=[C:29]([CH2:31][C:32](O)=[O:33])[N:30]=1)[C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1>>[CH2:18]([NH:25][C:26]1[S:27][CH:28]=[C:29]([CH2:31][C:32]([NH:1][C:2]2[CH:3]=[CH:4][C:5]([CH2:8][CH2:9][NH:10][C:11](=[O:17])[O:12][C:13]([CH3:14])([CH3:16])[CH3:15])=[CH:6][CH:7]=2)=[O:33])[N:30]=1)[C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1

Participants

3

Reactant 2

HCID 382207Tert-butyl 4-aminophenethylcarbamateHCID 1133220HCID 1133220, compound

Product 1

HCID 54309575HCID 54309575, compound

Procedure

960 mg of t-butyl 2-(4-aminophenyl)ethylcarbamate and (2-benzylaminothiazol-4-yl)acetic acid were subjected to an amidation reaction to obtain 500 mg of t-butyl [2-[4-[2-(2-benzylaminothiazol-4-yl)acetylamino]phenyl]ethyl]carbamate.

Sources & evidence

ORD record
ord-59044d5e29c34df8a9ce5033d5db44e3
Source dataset
uspto-grants-2000_04
Patent number
US06048884

Reaction notes

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