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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1004177Generated: November 1, 2026

Water → HCID 23434143, compound

https://huagongshe.com/reaction/1004177

Reaction equation

Participants

RoleNameHCIDCharge
ReactantWaterHCID 962—
ReactantPotassium HydroxideHCID 14797—
ReactantHCID 12112779HCID 12112779—
Solventtert-ButanolHCID 6386—
ProductHCID 23434143HCID 2343414370.2%

Reaction Steps

A mixture of 3-cyano-2,5-di(4-pyridyl)thiophene (40 mg, 0.152 mmol), potassium hydroxide (25 mg, 0.446 mmol) in 2-methyl-2-propanol (2 mL) was heated at reflux temperature for 2 hours. After cooling, the mixture was poured into water. The precipitates were collected by filtration, and dried under reduced pressure to give the title compound (30 mg, 70% yield).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06048880
Source datasetuspto-grants-2000_04
ORD IDord-9d2fc2310717420d93a603f053092681
Source noteuspto-grants-2000_04