HRID1004337

反应详情

EQUATION

反应方程式

REACTANTS

反应物

反应SMILES：CC(O)C(CO[Si](C)(C)C(C)(C)C)Cc1ccc(C(=O)Nc2ccccc2)o1

HCID18794886

未命名化合物

反应SMILES：CCOC(=O)c1ccc(CC(C(=O)OC(C)(C)C)C(C)NCc2ccc3ccccc3c2)o1

HCID54102143

未命名化合物

PRODUCTS

产物

反应SMILES：CC(NCc1ccc2ccccc2c1)C(CO[Si](C)(C)C(C)(C)C)Cc1ccc(C(=O)Nc2ccccc2)o1

HCID18794892

未命名化合物

PROCEDURE

实验过程

The title compound was prepared by the same reactions as in Reference Example 1(3) and (4) by using (2RS,3SR)-3-(tert-butyldimethylsilyloxymethyl)-2-hydroxy-4-{5-(phenylcarbamoyl)-2-furyl}butane instead of tert-butyl (2RS,3SR)-2-{5-(ethoxycarbonyl)-2-furylmethyl}-3-hydroxybutanoate used as the starting material in Reference Example 1(3).

来源与证据

来源类型: Open Reaction Database
ORD记录: ord-2ab5ea2920f14f4e95fe5ffe4db57764
来源数据集: uspto-grants-2000_04
DOI: 10.6084/m9.figshare.5104873.v1
专利号: US06048894
来源说明: uspto-grants-2000_04

反应SMILES

C(OC(C1OC(CC(C([NH:22][CH2:23][C:24]2[CH:33]=[CH:32][C:31]3[C:26](=[CH:27][CH:28]=[CH:29][CH:30]=3)[CH:25]=2)C)C(OC(C)(C)C)=O)=CC=1)=O)C.[Si:34]([O:41][CH2:42][CH:43]([CH2:47][C:48]1[O:49][C:50]([C:53](=[O:61])[NH:54][C:55]2[CH:60]=[CH:59][CH:58]=[CH:57][CH:56]=2)=[CH:51][CH:52]=1)[CH:44](O)[CH3:45])([C:37]([CH3:40])([CH3:39])[CH3:38])([CH3:36])[CH3:35]>>[CH:25]1[C:26]2[C:31](=[CH:30][CH:29]=[CH:28][CH:27]=2)[CH:32]=[CH:33][C:24]=1[CH2:23][NH:22][CH:44]([CH3:45])[CH:43]([CH2:42][O:41][Si:34]([C:37]([CH3:38])([CH3:39])[CH3:40])([CH3:36])[CH3:35])[CH2:47][C:48]1[O:49][C:50]([C:53](=[O:61])[NH:54][C:55]2[CH:56]=[CH:57][CH:58]=[CH:59][CH:60]=2)=[CH:51][CH:52]=1