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HRID1004407

反应详情

EQUATION

反应方程式

HRID 1004407 的结构方程式

REACTANTS

反应物

3
结构：CC1CO1
HCID6378

(+/-)-1,2-Propylene oxide

C3H6O

结构：[Gd]
HCID23982

Gadolinium

Gd

结构：O=C([O-])CN1CCNCCN(CC(=O)[O-])CCN(CC(=O)[O-])CC1.[Na+].[Na+].[Na+]
HCID10862527

未命名化合物

PRODUCTS

生成物

1
结构：CC(O)CN1CCN(CC(=O)[O-])CCN(CC(=O)[O-])CCN(CC(=O)[O-])CC1.[Gd+3]
HCID60714

未命名化合物

PROCEDURE

实验过程

The solution of 1,4,7,10-tetraazacyclododecane-1,4,7-triacetic acid sodium salt is directly reacted, as described in EP 292689, with propylene oxide to give the alkylated product, which can easily be complexed with gadolinium to give the final Gadoteridol.

WORKUP

后处理

  1. customto give the alkylated product, which