4-Aminophenylacetic acid → HCID 86755325, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of MDTA-Cl X (2.18 g, 3.3 mmole) and p-aminophenylacetic acid (1.2 g, 8.27 mmole) in DMA (8 mL) was stirred at 60° C. for 30 h. The solvent was removed and the residue was treated with hot EtOAc (600 mL) containing EtOH (25 mL). The solution was filtered and the filtrate was freed of the solvent. The solid was recrystallized from EtOAc--EtOH to afford the title compound as a white amorphous solid (1.54 g, 57%).

Provenance & Evidence