m-Chloroperbenzoic acid → HCID 18792758, compound

Participants

Reaction Steps

The title compound (0.24 g, 45%) was prepared by the above general procedure using 2-[[3-methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl]methylthio]-6-fluoro-5-(imidazol-1-yl)-1H-benzimidazole (0.5 g, 1.14 mmol) (obtained in example 2), m-chloroperbenzoic acid (50%, 0.47 g, 1.4 mmol) and dichloromethane (10 mL). mp 234-235° C.; IR (KBr) 3449, 1049 cm- 1; 1H NMR (CD3OD+CDCl3) δ 2.28 (s, 3H, CH3), 4.42 (q,J=6.3 Hz, 2H, OCH2CF3), 4.74 (ABq, J=9.6 Hz, Δv=6.2 Hz, 2H, SOCH2), 6.74 (d,J=5.6 Hz, 1H), 7.20 (m, 2H), 7.52 (d,J=10.8 Hz, 1H), 7.70 (d,J=7.6 Hz, 1H), 7.86 (s, 1H), 8.30 (d,J=5.6 Hz, 1H); Mass (m/z) 453 (M+).

Provenance & Evidence