HCID 21925692, compound → HCID 21925676, compound

Participants

Reaction Steps

Dimethyl 2-[2-nitro-4-(3-trifluoroacetamidophenyl)phenyl]malonate (4.4 g) was refluxed overnight in 50 mL 6 N hydrochloric acid. The reaction mixture was cooled to room temperature and the solids were collected by vacuum filtration, washed with water, and dried under vacuum to give 2.7 g (73% yield) of 2-[2-nitro-4-(3-trifluoroacetamidophenyl)phenyl]acetic acid.

Provenance & Evidence