Acetic Anhydride → 3-Acetoxy-2-methylbenzoic acid

HRID 1004797Notes

Reaction equation

[Na][Na].[OH:3][C:4]1[C:5]([CH3:13])=[C:6]([CH:10]=[CH:11][CH:12]=1)[C:7]([OH:9])=[O:8].[C:14](OC(=O)C)(=[O:16])[CH3:15]>>[C:14]([O:3][C:4]1[C:5]([CH3:13])=[C:6]([CH:10]=[CH:11][CH:12]=1)[C:7]([OH:9])=[O:8])(=[O:16])[CH3:15]

Participants

Reactant 3

HCID 7918Acetic Anhydride

HCID 141233Disodium

HCID 2520233-Hydroxy-2-methylbenzoic Acid

Product 1

HCID 37985573-Acetoxy-2-methylbenzoic acid

Procedure

The disodium salt of 3-hydroxy-2-methylbenzoic acid (2) is reacted with acetic anhydride without intermediate isolation to give 3-acetoxy-2-methylbenzoic acid (3) ##STR3##

Sources & evidence

ORD record: ord-6040573842ce482d86899cfea9197a74
Source dataset: uspto-grants-2000_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06051732

Reaction notes

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