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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1005099Generated: October 30, 2026

HCID 22126520, compound → HCID 86604443, compound

https://huagongshe.com/reaction/1005099

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 22126520HCID 22126520—
ReactantHCID 54217560HCID 54217560—
ProductHCID 86604443HCID 86604443—

Reaction Steps

Alkylation of tert-butyl (1RS,2RS,3RS,5RS)-3-(4-fluoro-phenyl)-2-hydroxy-8-aza-bicyclo[3.2.1]octane-8-carboxylate with 1-benzyloxy-3-chloromethyl-naphthalene (Example 19) analogously to the procedure described in Example 1(g) yielded tert-butyl (1RS,2RS,3RS,5SR)-2-(4-benzyloxy-naphthalen-2-ylmethoxy)-3-(4-fluoro-phenyl)-8-aza-bicyclo[3.2.1]octane-8-carboxylate as a colourless solid; MS: 568 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06051712
Source datasetuspto-grants-2000_04
ORD IDord-20752580b9d74bdeb4d5222844d57d0d
Source noteuspto-grants-2000_04