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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1005103Generated: October 30, 2026

3-(Chloromethyl)pyridine → HCID 53797482, compound

https://huagongshe.com/reaction/1005103

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(Chloromethyl)pyridineHCID 18358—
Reactanttert-butyl (3RS,4RS)-4-(4-(2-hydroxy-ethoxy)-phenyl]-3-(naphthalen-2-ylmethoxy)-piperidine-1-carboxylateHCID 54366502—
ProductHCID 53797482HCID 53797482—

Reaction Steps

In an analogous manner to that described in Example 1 (g) by alkylating tert-butyl (3RS,4RS)-4-(4-(2-hydroxy-ethoxy)-phenyl]-3-(naphthalen-2-ylmethoxy)-piperidine-1-carboxylate [Example 53 (c)] with 3-chloromethyl-pyridine there was obtained tert-butyl (3RS,4RS)-3-(naphthalen-2-ylmethoxy)-4-{4-[2-(pyridin-3-ylmethoxy)-ethoxy]-phenyl}-piperidine-1-carboxylate; MS: 569 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06051712
Source datasetuspto-grants-2000_04
ORD IDord-3eea02f34da74656b75eedeb3c522e9a
Source noteuspto-grants-2000_04