HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(Bromomethyl)benzophenone → HCID 86604453, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(Bromomethyl)benzophenone | HCID 89586 | — |
| Reactant | Tert-butyl 4-(4-fluorophenyl)-3-hydroxypiperidine-1-carboxylate | HCID 45074236 | — |
| Product | HCID 86604453 | HCID 86604453 | — |
Reaction Steps
(jj) In an analogous manner to that described in Example 1 (g), by alkylating tert-butyl (3RS,4RS)-4-(4-fluoro-phenyl)-3-hydroxy-piperidine-1-carboxylate [Example 3 (b)] with (3-bromomethyl-phenyl)-phenyl-methanone [J.Med.Chem. 1984, 27 (12), 1682-1690] there was obtained tert-butyl (3RS,4RS)-3-(3-benzoyl-benzyloxy)-4-(4-fluoro-phenyl)-piperidine-1-carboxylate as a yellowish liquid; MS: 490 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06051712 |
| Source dataset | uspto-grants-2000_04 |
| ORD ID | ord-d14e4ea9435a4665aec340cf3c26532f |
| Source note | uspto-grants-2000_04 |