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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1005138Generated: October 31, 2026

Hydrochloric Acid → HCID 22127290, compound

https://huagongshe.com/reaction/1005138

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 22128827HCID 22128827—
SolventMethanolHCID 887—
ProductHCID 22127290HCID 22127290—

Reaction Steps

In an analogous manner to that described in Example 22 (l), from tert-butyl 3RS,4SR)-4-[4-(3-benzyloxy-propoxy)-phenyl]-3-(naphthalen-2-yl-acetyl)-piperidine-1-carboxylate by cleavage of the BOC protecting group with hydrogen chloride in methanol there was obtained [(3RS,4SR)-4-[4-(3-benzyloxy-propoxy)-phenyl]-piperidin-3-yl]-2-naphthalen-2-yl-ethanone hydrochloride (1:1) in in the form of colourless crystals; MS: 494 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06051712
Source datasetuspto-grants-2000_04
ORD IDord-2418396db5014a3c96d3fcf743e062df
Source noteuspto-grants-2000_04