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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1005149Generated: October 30, 2026

7-(Bromomethyl)quinoline--hydrogen bromide (1/1) → HCID 53993008, compound

https://huagongshe.com/reaction/1005149

Reaction equation

Participants

RoleNameHCIDCharge
Reactant7-(Bromomethyl)quinoline--hydrogen bromide (1/1)HCID 21713086—
ReactantHCID 54071872HCID 54071872—
ProductHCID 53993008HCID 53993008—

Reaction Steps

By alkylating tert-butyl (3RS,4RS)-4-[4-(3-benzyloxy-propoxy)-phenyl]-3-hydroxy-piperidine-1-carboxylate [Example 86 (n)] with 7-bromomethyl-quinoline hydrobromide [J.Am.Chem.Soc. 77, 1054(1955)] analogously to Example 1 (g) there was obtained tert-butyl (3RS,4RS)-4-[4-(3-benzyloxy-propoxy)-phenyl]-3-(quinolin-7-ylmethoxy)-piperidine-1-carboxylate as a colourless oil; MS: 583 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06051712
Source datasetuspto-grants-2000_04
ORD IDord-4a82c6159b0e4aac835a5064b53b7921
Source noteuspto-grants-2000_04