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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1005203Generated: November 1, 2026

HCID 86604501, compound → HCID 22127910, compound

https://huagongshe.com/reaction/1005203

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 86604501HCID 86604501—
CatalystZinc bromideHCID 10421208—
ProductHCID 22127910HCID 22127910—

Reaction Steps

In an analogous manner to that described in Example 125 (h), from tert-butyl (3RS,4RS)-4-[2-(3-benzyloxy-propylamino)-pyrimidin-5-yl]-3-(naphthalen-2-ylmethoxy)-piperidine-1-carboxylate by cleavage of the BOC group by means of anhydrous zinc bromide there was obtained (3-benzyloxy-propyl)-{5-[(3RS,4RS)-3-(naphthalen-2-ylmethoxy)-piperidin-4-yl]-pyrimidin-2-yl}-amine in the form of a brownish gum; MS: 483 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06051712
Source datasetuspto-grants-2000_04
ORD IDord-d43aebc9c7cc44c581ed6bac05dd1fa9
Source noteuspto-grants-2000_04