Dichloromethane → HCID 86755341, compound

Participants

Reaction Steps

1.5 g (16 mmol) of dimethyl disulfide and 5.3 g (52 mmol) of tert-butyl nitrite were added to a solution of 2 g (5.3 mmol) of 3-(5-amino-2,4-dichlorophenyl)-1-methyl-4,5-di(trifluoromethyl)-1H-pyrazole in 30 ml of dichloromethane. The reaction mixture was subsequently stirred for 16 hours, whereupon it was washed with water and dilute sodium hydroxide solution, dried over magnesium sulfate and finally concentrated. The residue was purified by means of silica gel chromatography (eluent: hexane/ethyl acetate =4:1). Yield: 37%.

Provenance & Evidence